Very rare (may affect up to 1 in 10,000 people) High blood pressure Inflammation of the pancreas – the signs include serious upper stomach pain, often with feeling sick (nausea) or being sick (vomiting) Bleeding in the gut – shows as blood in stools or when being sick Seeing things that are not there (hallucinations) Some people who have been violently sick have had tearing of the tube that connects your mouth with your stomach (oesophagus)

Bloody or black tarry stools, vomiting blood Spontaneous bleeding or bruising (signs of thrombocytopenia) Shortness of breath, wheezing, any trouble breathing or chest tightness Skin rash, hives, swelling or itching Skin rash with flacking or peeling (signs of dermatitis exfoliative). Purple skin patches (signs of purpura or Henoch-Schonlein purpura if caused by an allergy). Blurred vision, or any visual disturbance Any change in the amount or colour of your urine (red or brown) Any pain or difficulty experienced while urinating Swelling of the feet, lower legs; weight gain Swelling mainly of the face and throat (signs of angioedema) Vo ...[+++]miting or persistent indigestion,

For the prevention of vomiting induced by motion sickness. For the prevention and treatment of vomiting, in conjunction with Cerenia Solution For Injection and in combination with other supportive measures.

normal, an increase in episodes of vomiting, blood in your vomit, stools (bowel movements) or urine, or have black stools (tarry black bowel movements).

of purpura or Henoch- Schonlein purpura if caused by an allergy). Blurred vision, or any visual disturbance Any change in the amount or colour of your urine (red or brown) Any pain or difficulty experienced while urinating Swelling of the feet, lower legs; weight gain Swelling mainly of the face and throat (signs of angioedema) Vomiting or persistent indigestion, nausea, stomach pain or diarrhea Yellow discolouration of the skin or eyes (signs of liver failure), with or without itchy skin Malaise, fatigue, loss of appetite or « flu-like » symptoms Headaches, stiff neck, fever, nausea, vomiting (signs of aseptic meningitis) Mental confus ...[+++]ion, depression

Diarrhoea and vomiting Treatment with bosutinib is associated with diarrhoea and vomiting, therefore patients with recent or ongoing clinically significant gastrointestinal disorder should use this medicinal product with caution and only after a careful benefit-risk assessment as respective patients were excluded from the clinical studies.