carcinogenic substances and preparations: substances or preparations which, if they are inhaled or ingested or if they penetrate the skin, may induce cancer or increase its incidence;

Where appropriate the hazard analysis must address the risk resulting from the inhalation of the spray ejected by the aerosol dispenser under normal or reasonably foreseeable conditions of use, taking into account droplet size and size distribution in conjunction with physical and chemical properties of the contents, as the inhalation of small aerosol droplets may give rise to adverse health effects for the user under such conditions of use, even if the aerosol dispenser is properly classified and labelled according to the provisions of Directive 1999/45/EC of the European Parliament and of the Council of 31 May 1999 concerning the appro ...[+++]ximation of the laws, regulations and administrative provisions of the Member States relating to the classification, packaging and labelling of dangerous preparations (2).

concerns for testicular effects, fertility, toxicity to kidneys on repeated exposure, and developmental toxicity as a consequence of inhalation and dermal exposure during production, processing and industrial end-use of preparations or materials containing DEHP.

concerns for general systemic toxicity, carcinogenicity and reproductive toxicity as a consequence of inhalation and dermal exposure arising from manufacture and use (intermediate, formulation of products containing the substance and production of grinding wheels),

concerns for local effects as a consequence of repeated inhalation exposure arising during the formulation of preparations containing 2-ethylhexyl acrylate.

concerns for acute toxicity (neurobehavioural effects) and general systemic toxicity (hepatic effects) as a consequence of inhalation exposure arising from formulation and industrial use of products containing the substance as well as from use of products containing the substance in craft industries.