Analysis of splenic lymphocyte subpopulations in non-immunised (cohort 1A) animals will determine if exposure is related to a shift in the immunological steady state distribution of “helper” (CD4+) or cytotoxic (CD8+) thymus-derived lymphocytes or natural killer (NK) cells (rapid responses to neoplastic cells and pathogens).

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L'analyse des sous-populations lymphocytaires spléniques chez les animaux non immunisés (cohorte 1A) déterminera si l'exposition contribue à une modification de l'équilibre immunologique concernant la distribution des lymphocytes thymiques “auxiliaires” (CD4+) ou cytotoxiques (CD8+) ou des cellules tueuses naturelles (NK) (réponses rapides aux cellules néoplastiques et aux pathogènes).

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splenic lymphocyte subpopulation analysis (CD4+ and CD8+ T lymphocytes, B lymphocytes, and natural killer cells) using one half of the spleen, the other half of the spleen being preserved for histopathological evaluation,

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analyse des sous-populations lymphocytaires spléniques (lymphocytes T CD4+ et CD8+, lymphocytes B, et cellules tueuses naturelles NK) effectuée sur la moitié de la rate, l'autre moitié étant conservée en vue de l'examen histopathologique.

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'CD4 T cell'

Date index:2023-10-28 -

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Translation of "CD4 T cell " (English → French) :

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