maximum permissible dose equivalent | MPDE | mpde | maximum permissible dose | permissible dose | tolerance dose

tolerable daily intake

bone tolerance dose

Definition: This block contains a wide variety of disorders that differ in severity and clinical form but that are all attributable to the use of one or more psychoactive substances, which may or may not have been medically prescribed. The third character of the code identifies the substance involved, and the fourth character specifies the clinical state. The codes should be used, as required, for each substance specified, but it should be noted that not all fourth character codes are applicable to all substances. Identification of the psychoactive substance should be based on as many sources of information as possible. These include sel ...[+++]f-report data, analysis of blood and other body fluids, characteristic physical and psychological symptoms, clinical signs and behaviour, and other evidence such as a drug being in the patient's possession or reports from informed third parties. Many drug users take more than one type of psychoactive substance. The main diagnosis should be classified, whenever possible, according to the substance or class of substances that has caused or contributed most to the presenting clinical syndrome. Other diagnoses should be coded when other psychoactive substances have been taken in intoxicating amounts (common fourth character .0) or to the extent of causing harm (common fourth character .1), dependence (common fourth character .2) or other disorders (common fourth character .3-.9). Only in cases in which patterns of psychoactive substance-taking are chaotic and indiscriminate, or in which the contributions of different psychoactive substances are inextricably mixed, should the diagnosis of disorders resulting from multiple drug use (F19.-) be used. | Modifiers The following fourth-character subdivisions are for use with categories F10-F19: Code Title .0 Acute intoxication A condition that follows the administration of a psychoactive substance resulting in disturbances in level of consciousness, cognition, perception, affect or behaviour, o ...

tolerable intake

Maximum dosage of nerve agent vapour to the eyes acceptable for aircrew

lethal dose | L.D.50 | median tolerance limit

Otherwise, reference values for acceptable or tolerable levels of intake, such as the acceptable daily intake (ADI) or tolerable upper intake level (UL), shall be considered in relation to the anticipated intake.

The Contam Panel established a group acute reference dose of 1 μg/kg body weight (‘b.w’. ) and a group tolerable daily intake of 0,6 μg/kg b.w.

Return to footnote When the equivalent dose received by and committed to one of these remainder organs and tissues exceeds the equivalent dose received by and committed to any one of the organs and tissues listed in items 1 to 12, a weighting factor of 0.025 shall be applied to that remainder organ or tissue and a weighting factor of 0.025 shall be applied to the average equivalent dose received by and committed to the rest of the remainder organs and tissues.

On individual occasions, consumption of sheep liver could result in high intakes exceeding the tolerable weekly intake (TWI) of those contaminants.