16. A variety of transgenic mouse gene mutation detection models are currently available, and these systems have been more widely used than transgenic rat models.

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16. On dispose actuellement de divers modèles de détection des mutations génétiques chez les souris transgéniques, et ces systèmes continuent d'être plus souvent utilisés que les modèles impliquant des rats transgéniques.

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Yauk, C.L., J.D. Gingerich, L. Soper, A. MacMahon, W.G. Foster and G.R. Douglas (2005), “A lacZ Transgenic Mouse Assay for the Detection of Mutations in Follicular Granulosa Cells”, Mutation Res., 578(1-2): 117-123.

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Yauk, C.L., Gingerich, J.D., Soper, L., MacMahon, A., Foster, W.G., et Douglas, G.R (2005), “A lacZ Transgenic Mouse Assay for the Detection of Mutations in Follicular Granulosa Cells”, Mutation Res, 578(1-2):117-123.

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Piegorsch, W.W., B.H. Margolin, M.D. Shelby, A. Johnson, J.E. French, R.W. Tennant and K.R. Tindall (1995), “Study Design and Sample Sizes for a lacI Transgenic Mouse Mutation Assay”, Environ.

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Piegorsch, W.W., Margolin, B.H., Shelby, M.D., Johnson, A., French, J.E., Tennant, R.W., et Tindall, K.R (1995), “Study Design and Sample Sizes for a lacI Transgenic Mouse Mutation Assay”, Environ. Mol.

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Nohmi, T., T. Suzuki and K.I. Masumura (2000), “Recent Advances in the Protocols of Transgenic Mouse Mutation Assays”, Mutation Res., 455(1–2): 191–215.

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Nohmi, T., Suzuki, T., et Masumura, K.I (2000), “Recent Advances in the Protocols of Transgenic Mouse Mutation Assays”, Mutation Res., 455(1-2):191-215.

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Boerrigter, M.E., M.E. Dollé, H.-J. Martus, J.A. Gossen and J. Vijg (1995), “Plasmid-based Transgenic Mouse Model for Studying in vivo Mutations”Nature, 377(6550): 657–659

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Boerrigter, M.E., Dollé, M.E., Martus, H.-J., Gossen, J.A., et Vijg, J (1995), “Plasmid-based Transgenic Mouse Model for Studying in vivo Mutations”, Nature, 377(6550):657-659

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The other place where human genes are in fact introduced into mouse cells on occasion is to look at what are called transgenic mice, where you put in a foreign gene, and sometimes those foreign genes are from other mice.

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Un autre exemple de gènes humains introduits dans des cellules de souris s'observe lorsqu'on étudie ce que nous appelons les souris transgéniques, et c'est essentiellement le fait d'introduire dans l'organisme d'une souris un gène étranger qui peut aussi être le gène d'une autre souris.

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